Human KLK11 protein (Recombinant-Active) (C-10*His) (STJP012309)

Name: Human KLK11 protein (Recombinant-Active) (C-10*His) (STJP012309)
SKU: STJP012309-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP012309-100

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Short Description	Recombinant-Active-Human KLK11-C-10His protein was developed from mammalian cells and has a target region of C-10His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	<0.1 EU/Mu g of the protein by the LAL method.
Immunoreactivity	Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxyLys-ThioBenzyl ester (Z-Lys-SBzl) , in the presence of 5, 5 Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is >200 pmol/min/µg, as measured under the

Post Translational Modifications	About 40% of KLK11 is inactivated by internal cleavage after Arg-188. This proteolytic inactivation may be effected by plasminogen.
Function	Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.
Protein Name	Kallikrein-11 Hk11 Hippostasin Serine Protease 20 Trypsin-Like Protease Cleaved Into - Kallikrein-11 Inactive Chain 1 - Kallikrein-11 Inactive Chain 2
Database Links
Cellular Localisation	Isoform 1: Secreted Isoform 2: Golgi Apparatus Secreted
Alternative Protein Names	Kallikrein-11 protein Hk11 protein Hippostasin protein Serine Protease 20 protein Trypsin-Like Protease Cleaved Into - Kallikrein-11 Inactive Chain 1 - Kallikrein-11 Inactive Chain 2 protein KLK11 protein PRSS20 protein TLSP protein UNQ649 protein PRO1279 protein

Information sourced from Uniprot.org