Human KLHDC8B protein (Recombinant) (His-Tag) (STJP018957)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human KLHDC8B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLHDC8B |
| Gene ID | 200942 |
| Uniprot ID | KLD8B_HUMAN |
| Accession Number | NP_775817 |
| Immunogen | Human |
| Immunogen Region | 1-354aa |
| Immunogen Sequence |
Additional Info
| Function | Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells. |
| Protein Name | Kelch Domain-Containing Protein 8b |
| Database Links | |
| Cellular Localisation | CytoplasmMidbodyIn Mitotic CellsConcentrates In The Midbody Of The Cytoplasmic Bridge Linking Daughter Cells As They Are About To Separate During Cytokinesis |
| Alternative Protein Names | Kelch Domain-Containing Protein 8b proteinKLHDC8B proteinFP17659 protein |
Information sourced from Uniprot.org