Human KIR3DS1/CD158e2 protein (Recombinant-Active) (C-hFc-His) (STJP012110)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human KIR3DS1/CD158e2-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability to bind HLA on human breast cancer cells (MDA‑MB‑231). The ED50 for this effect is 0.03-0.18 Mu g/mL. |
Target Information
| Gene Symbol | KIR3DS1 |
| Gene ID | 3813 |
| Uniprot ID | KI3S1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | His22-His340 |
Additional Info
| Function | Receptor on natural killer (NK) cells for MHC class I molecules. Upon interaction with peptide-free HLA-F open conformer, triggers NK cell degranulation and anti-viral cytokine production. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3ds1Natural Killer-Associated Transcript 10Nkat-10 |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Killer Cell Immunoglobulin-Like Receptor 3ds1 proteinNatural Killer-Associated Transcript 10 proteinNkat-10 proteinKIR3DS1 proteinNKAT10 protein |
Information sourced from Uniprot.org