Human KIN protein (Recombinant) (N-His) (STJP010715)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KIN-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KIN |
| Gene ID | 22944 |
| Uniprot ID | KIN17_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ile142 |
Additional Info
| Function | Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo. Binds via its C-terminal domain to RNA in vitro. |
| Protein Name | Dna/Rna-Binding Protein Kin17Binding To Curved DnaKin - Antigenic Determinant Of Reca Protein Homolog |
| Database Links | Reactome: R-HSA-8876725 |
| Cellular Localisation | NucleusCytoplasmDuring S PhaseStrongly Associated With The Nuclear MatrixAnd To Chromosomal Dna In The Presence Of Dna DamageAlso Shows Cytoplasmic Localization In Elongated Spermatids |
| Alternative Protein Names | Dna/Rna-Binding Protein Kin17 proteinBinding To Curved Dna proteinKin - Antigenic Determinant Of Reca Protein Homolog proteinKIN proteinBTCD proteinKIN17 protein |
Information sourced from Uniprot.org