Human KIF23 protein (Recombinant) (N-His) (STJP016029)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KIF23-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | KIF23 |
| Gene ID | 9493 |
| Uniprot ID | KIF23_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu22-Gln458 |
Additional Info
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP8/UBPY. |
| Function | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. |
| Protein Name | Kinesin-Like Protein Kif23Kinesin-Like Protein 5Mitotic Kinesin-Like Protein 1 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindleMidbodyMidbody RingLocalizes To The Interzone Of Mitotic SpindlesDetected At The Midbody During Later Stages Of Mitotic Cytokinesis |
| Alternative Protein Names | Kinesin-Like Protein Kif23 proteinKinesin-Like Protein 5 proteinMitotic Kinesin-Like Protein 1 proteinKIF23 proteinKNSL5 proteinMKLP1 protein |
Information sourced from Uniprot.org