Human KIF20A (Kinesin Family, Member 20A) Sandwich ELISA Kit (STJE0010154)
SPECIFICATIONS
General Information
| Short Description | This KIF20A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.049ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | KIF20A |
| Gene ID | 10112 |
| Uniprot ID | KI20A_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle. |
| Function | Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
| Protein Name | Kinesin-Like Protein Kif20aGg10_2Mitotic Kinesin-Like Protein 2Mklp2Rab6-Interacting Kinesin-Like ProteinRabkinesin-6 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
| Cellular Localisation | Golgi ApparatusCytoplasmCytoskeletonSpindleLocalizes To The Spindle Midzone During Anaphase And Telophase |
| Alternative ELISA Names | Kinesin-Like Protein Kif20a ELISA kitGg10_2 ELISA kitMitotic Kinesin-Like Protein 2 ELISA kitMklp2 ELISA kitRab6-Interacting Kinesin-Like Protein ELISA kitRabkinesin-6 ELISA kitKIF20A ELISA kitMKLP2 ELISA kitRAB6KIFL ELISA kit |
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Information sourced from Uniprot.org