Human KIF1B protein (Recombinant) (N-His) (STJP007999)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KIF1B-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KIF1B |
| Gene ID | 23095 |
| Uniprot ID | KIF1B_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Glu287 |
Additional Info
| Function | Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules. Isoform 2: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells. Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells. Isoform 3: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria. |
| Protein Name | Kinesin-Like Protein Kif1bKlp |
| Database Links | Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonHas A Plus-End-Directed Microtubule Motor Activity And Therefore Associates With MicrotubulesIsoform 2: Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneAssociates With Synaptic Vesicles And Mediates Their Anterograde Transport Along Axonal MicrotubulesIsoform 3: MitochondrionAssociates With Mitochondria And Mediates Their Movement Along Microtubules |
| Alternative Protein Names | Kinesin-Like Protein Kif1b proteinKlp proteinKIF1B proteinKIAA0591 proteinKIAA1448 protein |
Information sourced from Uniprot.org