Human KIF18A protein (Recombinant) (N-His) (STJP005736)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KIF18A-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KIF18A |
| Gene ID | 81930 |
| Uniprot ID | KI18A_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Lys453 |
Additional Info
| Function | Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. |
| Protein Name | Kinesin-Like Protein Kif18aMarrow Stromal Kif18aMs-Kif18a |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2132295Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-6811434Reactome: R-HSA-68877Reactome: R-HSA-9648025Reactome: R-HSA-983189 |
| Cellular Localisation | Cell ProjectionRuffleCytoplasmNucleusCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Protein Names | Kinesin-Like Protein Kif18a proteinMarrow Stromal Kif18a proteinMs-Kif18a proteinKIF18A proteinOK proteinSW-cl.108 protein |
Information sourced from Uniprot.org