Human KDSR protein (Recombinant) (His-Tag) (STJP017085)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human KDSR-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl, 0.1mM PMSF |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KDSR |
| Gene ID | 2531 |
| Uniprot ID | KDSR_HUMAN |
| Accession Number | NP_002026 |
| Immunogen | Human |
| Immunogen Region | 26-270aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes. |
| Function | Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis. |
| Protein Name | 3-Ketodihydrosphingosine ReductaseKds Reductase3-Dehydrosphinganine ReductaseFollicular Variant Translocation Protein 1Fvt-1Short Chain Dehydrogenase/Reductase Family 35c Member 1 |
| Database Links | Reactome: R-HSA-1660661 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | 3-Ketodihydrosphingosine Reductase proteinKds Reductase protein3-Dehydrosphinganine Reductase proteinFollicular Variant Translocation Protein 1 proteinFvt-1 proteinShort Chain Dehydrogenase/Reductase Family 35c Member 1 proteinKDSR proteinFVT1 proteinSDR35C1 protein |
Information sourced from Uniprot.org