Human KCNJ5 protein (Recombinant) (N-His) (STJP015757)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KCNJ5-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | KCNJ5 |
| Gene ID | 3762 |
| Uniprot ID | KCNJ5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser191-Pro381 |
Additional Info
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. This potassium channel is controlled by G proteins. |
| Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 4Girk-4Cardiac Inward RectifierCirHeart Katp ChannelInward Rectifier K(+ Channel Kir3.4Irk-4Katp-1Potassium Channel - Inwardly Rectifying Subfamily J Member 5 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | G Protein-Activated Inward Rectifier Potassium Channel 4 proteinGirk-4 proteinCardiac Inward Rectifier proteinCir proteinHeart Katp Channel proteinInward Rectifier K(+ Channel Kir3.4 proteinIrk-4 proteinKatp-1 proteinPotassium Channel - Inwardly Rectifying Subfamily J Member 5 proteinKCNJ5 proteinGIRK4 protein |
Information sourced from Uniprot.org