Human KCNE4 protein (Recombinant) (N-His-SUMO) (STJP008937)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KCNE4-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KCNE4 |
| Gene ID | 23704 |
| Uniprot ID | KCNE4_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | His2-Glu86 |
Additional Info
| Function | Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. Isoform 2: May inhibit KCNQ4-mediated potassium currents. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily E Member 4Mink-Related Peptide 3Mirp3Minimum Potassium Ion Channel-Related Peptide 3Potassium Channel Subunit Beta Mirp3 |
| Database Links | Reactome: R-HSA-5576890Reactome: R-HSA-5576893 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Protein Names | Potassium Voltage-Gated Channel Subfamily E Member 4 proteinMink-Related Peptide 3 proteinMirp3 proteinMinimum Potassium Ion Channel-Related Peptide 3 proteinPotassium Channel Subunit Beta Mirp3 proteinKCNE4 protein |
Information sourced from Uniprot.org