Human KCNE4 protein (Recombinant) (N-His-SUMO) (STJP008937)

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STJP008937
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human KCNE4-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KCNE4
Gene ID: 23704
Uniprot ID: KCNE4_HUMAN
Immunogen Region: His2-Glu86
Immunogen: Homo sapiens (Human)
Function Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. Isoform 2: May inhibit KCNQ4-mediated potassium currents.
Protein Name Potassium Voltage-Gated Channel Subfamily E Member 4
Mink-Related Peptide 3
Mirp3
Minimum Potassium Ion Channel-Related Peptide 3
Potassium Channel Subunit Beta Mirp3
Database Links Reactome: R-HSA-5576890
Reactome: R-HSA-5576893
Cellular Localisation Membrane
Single-Pass Membrane Protein
Alternative Protein Names Potassium Voltage-Gated Channel Subfamily E Member 4 protein
Mink-Related Peptide 3 protein
Mirp3 protein
Minimum Potassium Ion Channel-Related Peptide 3 protein
Potassium Channel Subunit Beta Mirp3 protein
KCNE4 protein

Information sourced from Uniprot.org

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