Human JPH3/JP-3 protein (Recombinant) (N-His) (STJP008519)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human JPH3/JP-3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | JPH3 |
| Gene ID | 57338 |
| Uniprot ID | JPH3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ser147 |
Additional Info
| Function | Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory. |
| Protein Name | Junctophilin-3Jp-3Junctophilin Type 3Trinucleotide Repeat-Containing Gene 22 Protein |
| Database Links | |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane ProteinLocalized Predominantly On The Plasma MembraneThe Transmembrane Domain Is Anchored In Endoplasmic Reticulum MembraneWhile The N-Terminal Part Associates With The Plasma Membrane |
| Alternative Protein Names | Junctophilin-3 proteinJp-3 proteinJunctophilin Type 3 proteinTrinucleotide Repeat-Containing Gene 22 Protein proteinJPH3 proteinJP3 proteinTNRC22 protein |
Information sourced from Uniprot.org