Human ITPA protein (Recombinant) (N-His) (STJP006693)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ITPA-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ITPA |
| Gene ID | 3704 |
| Uniprot ID | ITPA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala3-Arg180 |
Additional Info
| Function | Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. |
| Protein Name | Inosine Triphosphate PyrophosphataseItpaseInosine TriphosphataseNon-Canonical Purine Ntp PyrophosphataseNon-Standard Purine Ntp PyrophosphataseNucleoside-Triphosphate DiphosphataseNucleoside-Triphosphate PyrophosphataseNtpasePutative Oncogene Protein Hlc14-06-PXtp/Ditp Diphosphatase |
| Database Links | Reactome: R-HSA-74259Reactome: R-HSA-9755088 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Inosine Triphosphate Pyrophosphatase proteinItpase proteinInosine Triphosphatase proteinNon-Canonical Purine Ntp Pyrophosphatase proteinNon-Standard Purine Ntp Pyrophosphatase proteinNucleoside-Triphosphate Diphosphatase proteinNucleoside-Triphosphate Pyrophosphatase proteinNtpase proteinPutative Oncogene Protein Hlc14-06-P proteinXtp/Ditp Diphosphatase proteinITPA proteinC20orf37 proteinMy049 proteinOK proteinSW-cl.9 protein |
Information sourced from Uniprot.org