Human ITGB1BP3 protein (Recombinant) (His-Tag) (STJP017779)

Name: Human ITGB1BP3 protein (Recombinant) (His-Tag) (STJP017779)
SKU: STJP017779
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017779

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Short Description	Recombinant-Human ITGB1BP3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.25 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	NMRK2
Gene ID	27231
Uniprot ID	NRK2_HUMAN
Accession Number	NP_733778
Immunogen	Human
Immunogen Region	1-230aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MGSMKLIVGI GGMTNGGKTT LTNSLLRALP NCCVIHQDDF FKPQDQIAVG EDGFKQWDVL ESLDMEAMLD TVQAWLSSPQ KFARAHGVSV QPEASDTHIL LLEGFLLYSY KPLVDLYSRR YFLTVPYEEC KWRRSTRNYT VPDPPGLFDG HVWPMYQKYR QEMEANGVEV VYLDGMKSRE ELFREVLEDI QNSLLNRSQE SAPSPARP

Tissue Specificity	Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta.
Function	Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis.
Protein Name	Nicotinamide Riboside Kinase 2 Nrk 2 Nmr-K 2 Integrin Beta-1-Binding Protein 3 Muscle Integrin-Binding Protein Mibp Nicotinic Acid Riboside Kinase 2 Ribosylnicotinamide Kinase 2 Rnk 2 Ribosylnicotinic Acid Kinase 2
Database Links	Reactome: R-HSA-196807
Cellular Localisation
Alternative Protein Names	Nicotinamide Riboside Kinase 2 protein Nrk 2 protein Nmr-K 2 protein Integrin Beta-1-Binding Protein 3 protein Muscle Integrin-Binding Protein protein Mibp protein Nicotinic Acid Riboside Kinase 2 protein Ribosylnicotinamide Kinase 2 protein Rnk 2 protein Ribosylnicotinic Acid Kinase 2 protein NMRK2 protein ITGB1BP3 protein NRK2 protein

Information sourced from Uniprot.org