Human ITGa2 (Integrin Alpha 2) Sandwich ELISA Kit (STJE0010078)
SPECIFICATIONS
General Information
| Short Description | This ITGa2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.055ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | ITGA2 |
| Gene ID | 3673 |
| Uniprot ID | ITA2_HUMAN |
| Sample Type | tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8. |
| Protein Name | Integrin Alpha-2Cd49 Antigen-Like Family Member BCollagen ReceptorPlatelet Membrane Glycoprotein IaGpiaVla-2 Subunit AlphaCd Antigen Cd49b |
| Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000157Reactome: R-HSA-3000170Reactome: R-HSA-3000178Reactome: R-HSA-447041Reactome: R-HSA-75892Reactome: R-HSA-8874081Reactome: R-HSA-9926550 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Integrin Alpha-2 ELISA kitCd49 Antigen-Like Family Member B ELISA kitCollagen Receptor ELISA kitPlatelet Membrane Glycoprotein Ia ELISA kitGpia ELISA kitVla-2 Subunit Alpha ELISA kitCd Antigen Cd49b ELISA kitITGA2 ELISA kitCD49B ELISA kit |
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Information sourced from Uniprot.org