Human IREB2 protein (Recombinant) (N-His) (STJP004782)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human IREB2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | IREB2 |
| Gene ID | 3658 |
| Uniprot ID | IREB2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Pro39-Ser281 |
Additional Info
| Function | RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. |
| Protein Name | Iron-Responsive Element-Binding Protein 2Ire-Bp 2Iron Regulatory Protein 2Irp2 |
| Database Links | Reactome: R-HSA-917937 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Iron-Responsive Element-Binding Protein 2 proteinIre-Bp 2 proteinIron Regulatory Protein 2 proteinIrp2 proteinIREB2 protein |
Information sourced from Uniprot.org