Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer protein (Recombinant) (C-His&Avi) (STJP020314)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.οΌIt contains Phe31-Val992 (ITGAV) acidic tail&Gly22-Asn707 (ITGB6) basic tail.
General Information
| Short Description | Recombinant-Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer-C-His&Avi protein was developed in hek293 cells using the region NA. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.οΌIt contains Phe31-Val992 (ITGAV) acidic tail&Gly22-Asn707 (ITGB6) basic tail. |
Additional Info
| Background | ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. |
Information sourced from Uniprot.org