Human INPP5A protein (Recombinant) (C-His) (STJP013472)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human INPP5A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | INPP5A |
| Gene ID | 3632 |
| Uniprot ID | I5P1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Val410 |
Additional Info
| Post Translational Modifications | Isoprenylation at Cys-409 is required for localization at the membrane. |
| Function | Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells. |
| Protein Name | Inositol Polyphosphate-5-Phosphatase A43 Kda Inositol Polyphosphate 5-PhosphataseType I Inositol 1 -4 -5-Trisphosphate 5-Phosphatase5ptase |
| Database Links | Reactome: R-HSA-1855183 |
| Cellular Localisation | Cell MembraneLipid-AnchorCell ProjectionDendrite |
| Alternative Protein Names | Inositol Polyphosphate-5-Phosphatase A protein43 Kda Inositol Polyphosphate 5-Phosphatase proteinType I Inositol 1 -4 -5-Trisphosphate 5-Phosphatase protein5ptase proteinINPP5A protein5PTASE protein |
Information sourced from Uniprot.org