Human IMP3 protein (Recombinant) (His-Tag) (STJP018027)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human IMP3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IMP3 |
| Gene ID | 55272 |
| Uniprot ID | IMP3_HUMAN |
| Accession Number | NP_060755.1 |
| Immunogen | Human |
| Immunogen Region | 1-184aa |
| Immunogen Sequence |
Additional Info
| Function | Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | U3 Small Nucleolar Ribonucleoprotein Protein Imp3U3 Snornp Protein Imp3Brms2 |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Protein Names | U3 Small Nucleolar Ribonucleoprotein Protein Imp3 proteinU3 Snornp Protein Imp3 proteinBrms2 proteinIMP3 proteinC15orf12 proteinMRPS4 protein |
Information sourced from Uniprot.org