Human IL32 protein (Recombinant-Active) (No tag) (STJP011931)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human IL32-No tag protein was developed from e.coli and has a target region of No tag. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability to induce TNF alpha secretion by mouse monocyte/macrophage cells (RAW 264.7) under serum free conditions in the presence of muramyl dipeptide (MDP). The ED50 for this effect is less than 12 Mu g/mL. |
Target Information
| Gene Symbol | IL32 |
| Gene ID | 9235 |
| Uniprot ID | IL32_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Cys2-Asn131 |
Additional Info
| Function | Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. |
| Protein Name | Interleukin-32Il-32Natural Killer Cells Protein 4Tumor Necrosis Factor Alpha-Inducing Factor |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-9013423 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interleukin-32 proteinIl-32 proteinNatural Killer Cells Protein 4 proteinTumor Necrosis Factor Alpha-Inducing Factor proteinIL32 proteinNK4 proteinTAIF protein |
Information sourced from Uniprot.org