Human IL27RA protein (Recombinant) (N-His) (STJP005597)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human IL27RA-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | IL27RA |
| Gene ID | 9466 |
| Uniprot ID | I27RA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu123-Pro343 |
Additional Info
| Function | Receptor for IL27. Requires IL6ST/GP130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and CNTFR. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms. |
| Protein Name | Interleukin-27 Receptor Subunit AlphaIl-27 Receptor Subunit AlphaIl-27r Subunit AlphaIl-27r-AlphaIl-27raCytokine Receptor Wsx-1Cytokine Receptor-Like 1Type I T-Cell Cytokine ReceptorTccrZcytor1 |
| Database Links | Reactome: R-HSA-8984722Reactome: R-HSA-9020956 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-27 Receptor Subunit Alpha proteinIl-27 Receptor Subunit Alpha proteinIl-27r Subunit Alpha proteinIl-27r-Alpha proteinIl-27ra proteinCytokine Receptor Wsx-1 proteinCytokine Receptor-Like 1 proteinType I T-Cell Cytokine Receptor proteinTccr proteinZcytor1 proteinIL27RA proteinCRL1 proteinTCCR proteinWSX1 proteinUNQ296 proteinPRO336 protein |
Information sourced from Uniprot.org