Human IL22RA1 protein (Recombinant) (N-His) (STJP005701)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human IL22RA1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | IL22RA1 |
| Gene ID | 58985 |
| Uniprot ID | I22R1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln267-Gly565 |
Additional Info
| Post Translational Modifications | Ubiquitinated. |
| Function | Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. |
| Protein Name | Interleukin-22 Receptor Subunit Alpha-1Il-22 Receptor Subunit Alpha-1Il-22r-Alpha-1Il-22ra1Cytokine Receptor Class-Ii Member 9Cytokine Receptor Family 2 Member 9Crf2-9Zcytor11 |
| Database Links | Reactome: R-HSA-8854691 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-22 Receptor Subunit Alpha-1 proteinIl-22 Receptor Subunit Alpha-1 proteinIl-22r-Alpha-1 proteinIl-22ra1 proteinCytokine Receptor Class-Ii Member 9 proteinCytokine Receptor Family 2 Member 9 proteinCrf2-9 proteinZcytor11 proteinIL22RA1 proteinIL22R protein |
Information sourced from Uniprot.org