Human IL1RAPL1 protein (Recombinant) (C-Fc) (STJP013600)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP013600-100
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General Information

Short DescriptionRecombinant-Human IL1RAPL1-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin< 1 EU/µg as determined by LAL test.

Target Information

Gene SymbolIL1RAPL1
Gene ID11141
Uniprot IDIRPL1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionLeu19-Thr357

Additional Info

Function May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.
Protein Name Interleukin-1 Receptor Accessory Protein-Like 1
Il-1-Rapl-1
Il-1rapl-1
Il1rapl-1
Oligophrenin-4
Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2
Tigirr-2
X-Linked Interleukin-1 Receptor Accessory Protein-Like 1
Database Links Reactome: R-HSA-388844
Reactome: R-HSA-9007892
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasm
Cell Projection
Axon
Dendrite
May Localize To The Cell Body And Growth Cones Of Dendrite-Like Processes
Alternative Protein Names Interleukin-1 Receptor Accessory Protein-Like 1 protein
Il-1-Rapl-1 protein
Il-1rapl-1 protein
Il1rapl-1 protein
Oligophrenin-4 protein
Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2 protein
Tigirr-2 protein
X-Linked Interleukin-1 Receptor Accessory Protein-Like 1 protein
IL1RAPL1 protein
OPHN4 protein

Information sourced from Uniprot.org

Citations

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