Human IL1F10 protein (Recombinant) (N-His) (STJP016257)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP016257
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General Information

Short DescriptionRecombinant-Human IL1F10-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
EndotoxinPlease contact us for further information.

Target Information

Gene SymbolIL1F10
Gene ID84639
Uniprot IDIL1FA_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionMet1-Trp152

Additional Info

Function Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
Protein Name Interleukin-1 Family Member 10
Il-1f10
Family Of Interleukin 1-Theta
Fil1 Theta
Interleukin-1 Hy2
Il-1hy2
Interleukin-1 Theta
Il-1 Theta
Interleukin-38
Il-38
Database Links Reactome: R-HSA-9007892
Reactome: R-HSA-9014826
Cellular Localisation Cytoplasm
Secreted
The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10
It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Protein Names Interleukin-1 Family Member 10 protein
Il-1f10 protein
Family Of Interleukin 1-Theta protein
Fil1 Theta protein
Interleukin-1 Hy2 protein
Il-1hy2 protein
Interleukin-1 Theta protein
Il-1 Theta protein
Interleukin-38 protein
Il-38 protein
IL1F10 protein
FIL1T protein
IL1HY2 protein
IL38 protein
FKSG75 protein
UNQ6119 protein
PRO20041 protein

Information sourced from Uniprot.org

Citations

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