Human IL-9 (IL-9) Antibody Pair (STJAP00729)
General Information
| Short Description | This IL-9 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R06-9L6/R07-8Q5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | IL9 |
| Gene ID | 3578 |
| Uniprot ID | IL9_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Function | Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs. Induction of differentiation genes seems to be mediated by STAT1 alone, while protection of cells from apoptosis depends on STAT3 and STAT5. |
| Protein Name | Interleukin-9Il-9Cytokine P40T-Cell Growth Factor P40 |
| Database Links | Reactome: R-HSA-8985947 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Interleukin-9 antibody pairIl-9 antibody pairCytokine P40 antibody pairT-Cell Growth Factor P40 antibody pairIL9 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human IL-9 (IL-9) Antibody Pair (STJAP00729)
This antibody pair is designed to detect human Interleukin-9 (IL-9), corresponding to UniProt entry P15248. Reactivity has been confirmed for human samples only.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated at 1 mg/mL in 0.01M PBS, pH 7.2. Neither antibody carries a conjugate or tag, so the user is responsible for labeling the detection antibody as required for their assay setup.
This pair has been validated for use in ELISA. No other assay formats are listed in the product specifications.
The two clones provided are R06-9L6 and R07-8Q5, both rabbit monoclonal antibodies raised against recombinant human IL-9 protein. Both were purified by affinity chromatography.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C. Repeated freeze/thaw cycles should be avoided to maintain antibody integrity.
Working concentrations are not predefined in the product specifications and must be determined empirically by the end user. Titration experiments are recommended to establish optimal coating and detection concentrations for the specific assay conditions being used.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.