Human IL-21 (Interleukin-21) Antibody Pair (STJAP00453)
General Information
| Short Description | This IL-21 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | IL21 |
| Gene ID | 59067 |
| Uniprot ID | IL21_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human IL-21 protien.Detection Immunogen: Recombinant Human IL-21 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Function | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. |
| Protein Name | Interleukin-21Il-21Za11 |
| Database Links | Reactome: R-HSA-9020958 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Interleukin-21 antibody pairIl-21 antibody pairZa11 antibody pairIL21 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human IL-21 (Interleukin-21) Antibody Pair (STJAP00453)
This antibody pair detects human IL-21 (Interleukin-21, UniProt Q9HBE4) and is validated for human reactivity only. Both the capture and detection antibodies were raised against recombinant human IL-21 protein.
The capture antibody is supplied unconjugated at 0.5 mg/mL in PBS with 0.04% Proclin 300 and 50% glycerol (pH 7.5), while the detection antibody is biotinylated and supplied at 0.5 mg/mL in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol (pH 7.5). Both antibodies are rabbit-raised and purified by antigen affinity.
This pair is validated for use in ELISA. It is intended for sandwich ELISA development using the unconjugated antibody as the capture component and the biotinylated antibody as the detection component.
The recommended sample types include serum, plasma, and other biological fluids. This product is for research use only and is not intended for diagnostic or therapeutic applications.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided, so it is advisable to prepare working aliquots upon first use.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.