Human IL-2 R beta/CD122 protein (Recombinant) (C-His&Avi) {Biotin} (STJP019907)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human IL-2 R beta/CD122 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala27-Asp239) of Human IL-2 R beta/CD122 (Accession #P14784) fused with a C-His&Avi tag at the C-te
General Information
| Short Description | Recombinant-Human IL-2 R beta/CD122-C-His&Avi protein was developed in hek293 cells using the region Ala27-Asp239. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | IL2RB |
| Gene ID | 3560 |
| Uniprot ID | IL2RB_HUMAN |
| Immunogen | Biotinylated Recombinant Human IL-2 R beta/CD122 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala27-Asp239) of Human IL-2 R beta/CD122 (Accession #P14784) fused with a C-His&Avi tag at the C-te |
| Immunogen Region | Ala27-Asp239 |
| Immunogen Sequence | AVNGTSQFTCFYNSRANISC VWSQDGALQDTSCQVHAWPD RRRWNQTCELLPVSQASWAC NLILGAPDSQKLTTVDIVTL RVLCREGVRWRVMAIQDFKP FENLRLMAPISLQVVHVETH RCNISWEISQASHYFERHLE FEARTLSPGHTWEEAPLLTL KQKQEWICLETLTPDTQYEF QVRVKPLQGEFTTWSPWSQP LAFRTKPAALGKD |
Additional Info
| Function | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. |
| Protein Name | Interleukin-2 Receptor Subunit BetaIl-2 Receptor Subunit BetaIl-2r Subunit BetaIl-2rbHigh Affinity Il-2 Receptor Subunit BetaInterleukin-15 Receptor Subunit BetaP70-75P75Cd Antigen Cd122 |
| Database Links | Reactome: R-HSA-5673001Reactome: R-HSA-8983432Reactome: R-HSA-9020558Reactome: R-HSA-912526 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-2 Receptor Subunit Beta proteinIl-2 Receptor Subunit Beta proteinIl-2r Subunit Beta proteinIl-2rb proteinHigh Affinity Il-2 Receptor Subunit Beta proteinInterleukin-15 Receptor Subunit Beta proteinP70-75 proteinP75 proteinCd Antigen Cd122 proteinIL2RB proteinIL15RB protein |
Information sourced from Uniprot.org