Human IL-2 R alpha/CD25 protein (Recombinant) (C-His&Avi) {Biotin} (STJP019910)

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STJP019910-100
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Short Description :Recombinant-Human IL-2 R alpha/CD25-C-His&Avi protein was developed in hek293 cells using the region Glu22-Cys213. For use in research applications.
Host:HEK293 cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Biotin
Formulation:Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:< 1 EU/Mu g of the protein by LAL method.
Gene Symbol:IL2RA
Gene ID:3559
Uniprot ID:IL2RA_HUMAN
Immunogen:Biotinylated Recombinant Human IL-2 R alpha/CD25 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu22-Cys213) of Human IL-2 R alpha/CD25 (Accession #P01589) fused with a C-His&Avi tag at the C-te
Immunogen Region:Glu22-Cys213
Immunogen Sequence:ELCDDDPPEIPHATFKAMAY KEGTMLNCECKRGFRRIKSG SLYMLCTGNSSHSSWDNQCQ CTSSATRNTTKQVTPQPEEQ KERKTTEMQSPMQPVDQASL PGHCREPPPWENEATERIYH FVVGQMVYYQCVQGYRALHR GPAESVCKMTHGKTRWTQPQ LICTGEMETSQFPGEEKPQA SPEGRPESETSC
Function Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
Protein Name Interleukin-2 Receptor Subunit Alpha
Il-2 Receptor Subunit Alpha
Il-2-Ra
Il-2r Subunit Alpha
Il2-Ra
Tac Antigen
P55
Cd Antigen Cd25
Database Links Reactome: R-HSA-5673001
Reactome: R-HSA-8877330
Reactome: R-HSA-9020558
Reactome: R-HSA-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-2 Receptor Subunit Alpha protein
Il-2 Receptor Subunit Alpha protein
Il-2-Ra protein
Il-2r Subunit Alpha protein
Il2-Ra protein
Tac Antigen protein
P55 protein
Cd Antigen Cd25 protein
IL2RA protein

Information sourced from Uniprot.org

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