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Human IL-1RN protein (Recombinant) (C-His) (STJP000776)

Human IL-1RN protein (Recombinant) (C-His) (STJP000776)
Human IL-1RN protein (Recombinant) (C-His) (STJP000776)
Human IL-1RN protein (Recombinant) (C-His) (STJP000776)
Human IL-1RN protein (Recombinant) (C-His) (STJP000776)

Human IL-1RN protein (Recombinant) (C-His) (STJP000776)

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STJP000776

€90.63 - €195.63

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General Information
Product Properties
Target Information
Additional Info
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Host:	E. coli
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human IL-1RN-C-His protein was developed from e. coli and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity:	Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human IL1RN at 10 Mu g/mL (100 Mu L/well) can bind Recombinant Human IL1R2 with a linear range of 0.4-1.8 Mu g/mL.

Gene Symbol:	IL1RN
Gene ID:	3557
Uniprot ID:	IL1RA_HUMAN
Immunogen Region:	Arg26-Glu177
Immunogen:	Recombinant Human IL-1RN Protein is produced by E. coli expression system. The target protein is expressed with sequence (Arg26-Glu177) of human IL-1RN (Accession #NP_776214.1) fused with an initial Met at the N-terminus and a 6×His tag at the C-term

Tissue Specificity	The intracellular form of IL1RN is predominantly expressed in epithelial cells.
Function	Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Protein Name	Interleukin-1 Receptor Antagonist Protein Il-1rn Il-1ra Irap Icil-1ra Il1 Inhibitor Anakinra
Database Links	Reactome: R-HSA-6783783 Reactome: R-HSA-9020702
Cellular Localisation	Isoform 1: Secreted Isoform 2: Cytoplasm Isoform 3: Cytoplasm Isoform 4: Cytoplasm
Alternative Protein Names	Interleukin-1 Receptor Antagonist Protein protein Il-1rn protein Il-1ra protein Irap protein Icil-1ra protein Il1 Inhibitor protein Anakinra protein IL1RN protein IL1F3 protein IL1RA protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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