SDS-PAGE gel of recombinant human IL-19 protein under reducing conditions Coomassie blue stain

Human IL-19 protein (Recombinant) (His-Tag) (STJP019469)

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STJP019469
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Short Description :Recombinant-Human IL-19-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:HEK293 Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin:< 1 EU per 1ug of protein (determined by LAL method)
Gene Symbol:IL19
Gene ID:29949
Uniprot ID:IL19_HUMAN
Accession Number:NP_037503.2
Immunogen:Human
Immunogen Region:25-177aa
Immunogen Sequence:LRRCL ISTDMHHIEE SFQEIKRAIQ AKDTFPNVTI LSTLETLQII KPLDVCCVTK NLLAFYVDRV FKDHQEPNPK ILRKISSIAN SFLYMQKTLR QCQEQRQCHC RQEATNATRV IHDNYDQLEV HAAAIKSLGE LDVFLAWINK NHEVMFSA
Function Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL13. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3.
Protein Name Interleukin-19
Il-19
Melanoma Differentiation-Associated Protein-Like Protein
Ng.1
Database Links Reactome: R-HSA-8854691
Cellular Localisation Secreted
Alternative Protein Names Interleukin-19 protein
Il-19 protein
Melanoma Differentiation-Associated Protein-Like Protein protein
Ng.1 protein
IL19 protein
ZMDA1 protein

Information sourced from Uniprot.org

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