• Human IL-18BP protein (Recombinant) (C-hFc&His) (STJP000937)
  • Human IL-18BP protein (Recombinant) (C-hFc&His) (STJP000937)
  • Human IL-18BP protein (Recombinant) (C-hFc&His) (STJP000937)
  • Human IL-18BP protein (Recombinant) (C-hFc&His) (STJP000937)

Human IL-18BP protein (Recombinant) (C-hFc&His) (STJP000937)

SKU:
STJP000937

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human IL-18BP-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human IL18BP at 2 Mu g/mL (100 Mu L/well) can bind IL18 with a linear range of 0.128-47.02 ng/mL.
Gene Symbol: IL18BP
Gene ID: 10068
Uniprot ID: I18BP_HUMAN
Immunogen Region: Thr31-Gly194
Immunogen: Recombinant Human IL-18BP Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Thr31-Gly194) of human IL18BPa (Accession #NP_001034748.1) fused with an Fc, 6×His tag at the C-terminus.
Tissue Specificity Strongly expressed in heart, lung, placenta and spleen.
Post Translational Modifications N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).N-glycan at Asn-147: dHex1Hex5HexNAc4.
Function Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Protein Name Interleukin-18-Binding Protein
Il-18bp
Tadekinig-Alfa
Database Links Reactome: R-HSA-9008059
Reactome: R-HSA-9012546
Cellular Localisation Secreted
Alternative Protein Names Interleukin-18-Binding Protein protein
Il-18bp protein
Tadekinig-Alfa protein
IL18BP protein

Information sourced from Uniprot.org

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