Human IL-13Ra1 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001621)
SPECIFICATIONS
HostHEK293
ConjugationBiotin
ImmunogenDNA sequence encoding Human IL-13Ra1 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
General Information
| Short Description | Recombinant-Human IL-13Ra1-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Dilution Range | Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
| Formulation | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Storage Instruction | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Target Information
| Gene Symbol | IL13RA1 |
| Gene ID | 3597 |
| Uniprot ID | I13R1_HUMAN |
| Immunogen | DNA sequence encoding Human IL-13Ra1 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
| Immunogen Region | Ala27-Thr343 |
Additional Info
| Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-1Il-13 Receptor Subunit Alpha-1Il-13r Subunit Alpha-1Il-13r-Alpha-1Il-13ra1Cancer/Testis Antigen 19Ct19Cd Antigen Cd213a1 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-13 Receptor Subunit Alpha-1 proteinIl-13 Receptor Subunit Alpha-1 proteinIl-13r Subunit Alpha-1 proteinIl-13r-Alpha-1 proteinIl-13ra1 proteinCancer/Testis Antigen 19 proteinCt19 proteinCd Antigen Cd213a1 proteinIL13RA1 proteinIL13R proteinIL13RA protein |
Information sourced from Uniprot.org