| Short Description : | Recombinant-Human IL-12/IL-12A&IL-12B-C-His＆C-Flag protein was developed in hek293 cells using the region Arg23-Ser219. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is 0.94-3.75 ng/mL, corresponding to a specific activity of 2.67×105~1.06×106 units/m |
| Determination Method: | <0.01 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | IL12AIL12B |
| Gene ID: | 35923593 |
| Uniprot ID: | IL12A_HUMANIL12B_HUMAN |
| Immunogen: | Recombinant Human IL-12/IL-12A&IL-12B Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (IL12B (Ile23-Ser328)-3 ( GGGGS ) IL12A (Arg23-Ser219) ) of Human IL-12/IL-12A&IL-12B (Accession #) fused with |
| Immunogen Region: | Arg23-Ser219 |
| Immunogen Sequence: | AGVGVGGPNICTTRGVSSCQ QCLAVSPMCAWCSDEALPLG SPRCDLKENLLKDNCAPESI EFPVSEARVLEDRPLSDKGS GDSSQVTQVSPQRIALRLRP DDSKNFSIQVRQVEDYPVDI YYLMDLSYSMKDDLWSIQNL GTKLATQMRKLTSNLRIGFG AFVDKPVSPYMYISPPEALE NPCYDMKTTCLPMFGYKHVL TLTDQVTRFNEEVKKQSVSR NRDAPEGGFDAIMQATVCD |
