This IGHG3 Sandwich ELISA is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma and other biological fluids.
Applications
ELISA
Reactivity
Human
Sensitivity
18.75ng/mL
Detection Limit
31.25~2000ng/mL
Note
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Product Properties
Storage Instruction
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
This kit recognizes Human IgG3 in samples. No significant cross-reactivity or interference between Human IgG3 and analogues was observed.
Sample Type
Serum, plasma and other biological fluids
Additional Info
Function
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Protein Name
Immunoglobulin Heavy Constant Gamma 3HdcHeavy Chain Disease ProteinIg Gamma-3 Chain C Region
Cellular Localisation
Isoform 1: SecretedIsoform 2: Cell MembraneSingle-Pass Membrane Protein
Alternative ELISA Names
Immunoglobulin Heavy Constant Gamma 3 ELISA kitHdc ELISA kitHeavy Chain Disease Protein ELISA kitIg Gamma-3 Chain C Region ELISA kitIGHG3 ELISA kit
Specificity
This kit recognizes Human IgG3 in samples. No significant cross-reactivity or interference between Human IgG3 and analogues was observed.
