Human IgG3 (Immunoglobulin Heavy Constant Gamma 3) Antibody Pair (STJAP00416)
SPECIFICATIONS
HostMouse/Mouse
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Natural Human IgG3 protien.Detection Immunogen: Natural Human IgG3 protien.
General Information
| Short Description | This IgG3 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Mouse |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Protein A or G. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | IGHG3Uniprot ID=IGHG3_HUMAN" |
| Immunogen | Capture immunogen: Natural Human IgG3 protien.Detection Immunogen: Natural Human IgG3 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Function | Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. |
| Protein Name | Immunoglobulin Heavy Constant Gamma 3HdcHeavy Chain Disease ProteinIg Gamma-3 Chain C Region |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: Cell MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Pair Names | Immunoglobulin Heavy Constant Gamma 3 antibody pairHdc antibody pairHeavy Chain Disease Protein antibody pairIg Gamma-3 Chain C Region antibody pairIGHG3 antibody pair |
Information sourced from Uniprot.org