Human IGFBP-rp1/IGFBP-7 protein (Recombinant) (His-Tag) (STJP018583)

Name: Human IGFBP-rp1/IGFBP-7 protein (Recombinant) (His-Tag) (STJP018583)
SKU: STJP018583
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018583

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Short Description	Recombinant-Human IGFBP-rp1/IGFBP-7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.25 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT, 1mM EDTA
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	IGFBP7
Gene ID	3490
Uniprot ID	IBP7_HUMAN
Accession Number	NP_001544
Immunogen	Human
Immunogen Region	27-282aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MGSSSSDTCG PCEPASCPPL PPLGCLLGET RDACGCCPMC ARGEGEPCGG GGAGRGYCAP GMECVKSRKR RKGKAGAAAG GPGVSGVCVC KSRYPVCGSD GTTYPSGCQL RAASQRAESR GEKAITQVSK GTCEQGPSIV TPPKDIWNVT GAQVYLSCEV IGIPTPVLIW NKVKRGHYGV QRTELLPGDR DNLAIQTRGG PEKHEVTG

Post Translational Modifications	N-glycosylated.
Function	Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis.
Protein Name	Insulin-Like Growth Factor-Binding Protein 7 Ibp-7 Igf-Binding Protein 7 Igfbp-7 Igfbp-Rp1 Mac25 Protein Pgi2-Stimulating Factor Prostacyclin-Stimulating Factor Tumor-Derived Adhesion Factor Taf
Database Links	Reactome: R-HSA-2559582 Reactome: R-HSA-381426 Reactome: R-HSA-8957275
Cellular Localisation	Secreted
Alternative Protein Names	Insulin-Like Growth Factor-Binding Protein 7 protein Ibp-7 protein Igf-Binding Protein 7 protein Igfbp-7 protein Igfbp-Rp1 protein Mac25 Protein protein Pgi2-Stimulating Factor protein Prostacyclin-Stimulating Factor protein Tumor-Derived Adhesion Factor protein Taf protein IGFBP7 protein MAC25 protein PSF protein

Information sourced from Uniprot.org