Human IGFBP-7 protein (Recombinant) (N-His) (STJP002393)

Name: Human IGFBP-7 protein (Recombinant) (N-His) (STJP002393)
SKU: STJP002393
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostHEK293 cells

ConjugationUnconjugated

ImmunogenRecombinant Human IGFBP-7 Protein Protein is expressed from Expi293 with His tag at the N-terminal.；It contains Asp30-Leu282

STJP002393

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Short Description	Recombinant-Human IGFBP-7-N-His protein was developed in hek293 cells using the region Asp30-Leu282. For use in research applications.
Host	HEK293 cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Formulation	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity	Measured by its binding ability in a functional ELISA. Immobilized human IGFBP7 at 2 Mu g/mL (100 Mu L/well) can bind human CD93 with a linear range of 0.17-290.4 ng/mL.
Determination Method	Less than 1 EU per Mu g by the LAL method.

Gene Symbol	IGFBP7
Gene ID	3490
Uniprot ID	IBP7_HUMAN
Immunogen	Recombinant Human IGFBP-7 Protein Protein is expressed from Expi293 with His tag at the N-terminal.；It contains Asp30-Leu282
Immunogen Region	Asp30-Leu282
Immunogen Sequence	DTCGPCEPASCPPLPPLGCL LGETRDACGCCPMCARGEGE PCGGGGAGRGYCAPGMECVK SRKRRKGKAGAAAGGPGVSG VCVCKSRYPVCGSDGTTYPS GCQLRAASQRAESRGEKAIT QVSKGTCEQGPSIVTPPKDI WNVTGAQVYLSCEVIGIPTP VLIWNKVKRGHYGVQRTELL PGDRDNLAIQTRGGPEKHEV TGWVLVSPLSKEDAGEYECH ASNSQGQASASAKITVVDA

Function	Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis.
Protein Name	Insulin-Like Growth Factor-Binding Protein 7 Ibp-7 Igf-Binding Protein 7 Igfbp-7 Igfbp-Rp1 Mac25 Protein Pgi2-Stimulating Factor Prostacyclin-Stimulating Factor Tumor-Derived Adhesion Factor Taf
Database Links	Reactome: R-HSA-2559582 Reactome: R-HSA-381426 Reactome: R-HSA-8957275
Cellular Localisation	Secreted
Alternative Protein Names	Insulin-Like Growth Factor-Binding Protein 7 protein Ibp-7 protein Igf-Binding Protein 7 protein Igfbp-7 protein Igfbp-Rp1 protein Mac25 Protein protein Pgi2-Stimulating Factor protein Prostacyclin-Stimulating Factor protein Tumor-Derived Adhesion Factor protein Taf protein IGFBP7 protein MAC25 protein PSF protein

Information sourced from Uniprot.org