Human IFNGR2 protein (Recombinant) (N-His) (STJP008341)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human IFNGR2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | IFNGR2 |
| Gene ID | 3460 |
| Uniprot ID | INGR2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys37-Asp240 |
Additional Info
| Function | Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. |
| Protein Name | Interferon Gamma Receptor 2Ifn-Gamma Receptor 2Ifn-Gamma-R2Interferon Gamma Receptor Accessory Factor 1Af-1Interferon Gamma Receptor Beta-ChainIfn-Gamma-R-BetaInterferon Gamma Transducer 1 |
| Database Links | Reactome: R-HSA-877300Reactome: R-HSA-877312Reactome: R-HSA-9679191Reactome: R-HSA-9732724 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmic Vesicle MembraneGolgi Apparatus MembraneEndoplasmic Reticulum MembraneCytoplasmHas Low Cell Surface Expression And High Cytoplasmic Expression In T CellsThe Bias Towards Cytoplasmic Expression May Be Due To Ligand-Independent Receptor Internalization And Recycling |
| Alternative Protein Names | Interferon Gamma Receptor 2 proteinIfn-Gamma Receptor 2 proteinIfn-Gamma-R2 proteinInterferon Gamma Receptor Accessory Factor 1 proteinAf-1 proteinInterferon Gamma Receptor Beta-Chain proteinIfn-Gamma-R-Beta proteinInterferon Gamma Transducer 1 proteinIFNGR2 proteinIFNGT1 protein |
Information sourced from Uniprot.org