Human IFN-alpha I/IFN17 protein (Recombinant) (C-6His) (STJP002938)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human IFN-alpha I/IFN17 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Asp189) of Human IFN-alpha I/IFN17 (Accession #NP_067091.1) fused with a His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human IFN-alpha I/IFN17-C-6His protein was developed in e.coli using the region Cys24-Asp189. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.17‑0.68 ng/mL, corresponding to a specific activity of 1.47×106~5.88×106 units/mg. |
| Determination Method | <0.01 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | IFNA17 |
| Gene ID | 3451 |
| Uniprot ID | IFN17_HUMAN |
| Immunogen | Recombinant Human IFN-alpha I/IFN17 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Asp189) of Human IFN-alpha I/IFN17 (Accession #NP_067091.1) fused with a His tag at the C-terminus. |
| Immunogen Region | Cys24-Asp189 |
| Immunogen Sequence | NWIDVRYDLEKIESLIQSIH IDTTLYTDSDFHPSCKVTAM NCFLLELQVILHEYSNMTLN ETVRNVLYLANSTLSSNKNV AESGCKECEELEEKTFTEFL QSFIRIVQMFINTS |
Additional Info
| Function | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Protein Name | Interferon Alpha-17Ifn-Alpha-17Interferon Alpha-88Interferon Alpha-I'Leif IInterferon Alpha-T |
| Database Links | Reactome: R-HSA-909733Reactome: R-HSA-912694Reactome: R-HSA-933541Reactome: R-HSA-9705671Reactome: R-HSA-983231Reactome: R-HSA-9833109 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interferon Alpha-17 proteinIfn-Alpha-17 proteinInterferon Alpha-88 proteinInterferon Alpha-I' proteinLeif I proteinInterferon Alpha-T proteinIFNA17 protein |
Information sourced from Uniprot.org