Human IFN-alpha G/IFNA5 protein (Recombinant) (C-hFC) (STJP003052)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human interferon-alpha/IFNA5 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu22-Glu189) of Human interferon-alpha/IFNA5 (Accession #NP_002160.1) fused with a His tag at the C-termin
General Information
| Short Description | Recombinant-Human IFN-alpha G/IFNA5-C-hFC protein was developed in hek293 cells using the region Leu22-Glu189. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 3.27‑13.06 ng/mL, corresponding to a specific activity of 7.66×104~3.06×105 units/mg. |
| Determination Method | <0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | IFNA5 |
| Gene ID | 3442 |
| Uniprot ID | IFNA5_HUMAN |
| Immunogen | Recombinant Human interferon-alpha/IFNA5 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu22-Glu189) of Human interferon-alpha/IFNA5 (Accession #NP_002160.1) fused with a His tag at the C-termin |
| Immunogen Region | Leu22-Glu189 |
| Immunogen Sequence | ASYVSNPICKGCLSCSKDNG CSRCQQKLFFFLRREGMRQY GECLHSCPSGYYGHRAPDMN RCARCRIENCDSCFSKDFCT KCKVGFYLHRGRCFDECPDG FAPLEETMECVEGCEVGHWS EWGTCSRNNRTCGFKWGLET RTRQIVKKPVKDTILCPTIA ESRRCKMTMRHCPG |
Additional Info
| Function | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Protein Name | Interferon Alpha-5Ifn-Alpha-5Interferon Alpha-61Interferon Alpha-GLeif G |
| Database Links | Reactome: R-HSA-909733Reactome: R-HSA-912694Reactome: R-HSA-933541Reactome: R-HSA-9705671Reactome: R-HSA-983231Reactome: R-HSA-9833109 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interferon Alpha-5 proteinIfn-Alpha-5 proteinInterferon Alpha-61 proteinInterferon Alpha-G proteinLeif G proteinIFNA5 protein |
Information sourced from Uniprot.org