Human IFN-alpha B2/IFNA8 protein (Recombinant) (N-His) (STJP003070)

SKU:
STJP003070

Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <0.01 EU/Mu g of the protein by LAL method.
Immunoreactivity: Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.10‑0.42 ng/mL, corresponding to a specific activity of 2.38×106~1.0×107 units/mg.
Gene Symbol: IFNA8
Gene ID: 3445
Uniprot ID: IFNA8_HUMAN
Immunogen Region: Ser24-Glu189
Immunogen: Recombinant Human IFN-alpha B2/IFNA8 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser24-Glu189) of Human IFN-alpha B2/IFNA8 (Accession #NP_002161.2) fused with a His tag at the C-terminus.
Immunogen Sequence: CCHPRLSLHRPALEDLLLGS EANLTCTLTGLRDASGVTFT WTPSSGKSAVQGPPERDLCG CYSVSSVLPGCAEPWNHGKT FTCTAAYPESKTPLTATLSK SGNTFRPEVHLLPPPSEELA LNELVTLTCLARGFSPKDVL VRWLQGSQELPREKYLTWAS RQEPSQGTTTFAVTSILRVA AEDWKKGDTFSCMVGHEALP LAFTQKTIDRLADWQMPPPY VVLDLPQETLEE
Function Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Protein Name Interferon Alpha-8
Ifn-Alpha-8
Interferon Alpha-B
Leif B
Interferon Alpha-B2
Database Links Reactome: R-HSA-909733
Reactome: R-HSA-912694
Reactome: R-HSA-933541
Reactome: R-HSA-9705671
Reactome: R-HSA-983231
Reactome: R-HSA-9833109
Cellular Localisation Secreted
Alternative Protein Names Interferon Alpha-8 protein
Ifn-Alpha-8 protein
Interferon Alpha-B protein
Leif B protein
Interferon Alpha-B2 protein
IFNA8 protein

Information sourced from Uniprot.org

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