Human IFN-alpha 21 protein (Recombinant) (N-His) (STJP003051)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human IFN-alpha 21 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Glu189) of Human IFN-alpha 21/IFNA21 (Accession #NP_002166.2) fused with a His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human IFN-alpha 21-N-His protein was developed in e.coli using the region Cys24-Glu189. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.50‑1.98 ng/mL, corresponding to a specific activity of 5.05×105~2.00×106 units/mg. |
| Determination Method | <0.01 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | IFNA21 |
| Gene ID | 3452 |
| Uniprot ID | IFN21_HUMAN |
| Immunogen | Recombinant Human IFN-alpha 21 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Glu189) of Human IFN-alpha 21/IFNA21 (Accession #NP_002166.2) fused with a His tag at the C-terminus. |
| Immunogen Region | Cys24-Glu189 |
| Immunogen Sequence | MPMFIVNTNVPRASVPDGFL SELTQQLAQATGKPPQYIAV HVVPDQLMAFGGSSEPCALC SLHSIGKIGGAQNRSYSKLL CGLLAERLRISPDRVYINYY DMNAANVGWNNSTFA |
Additional Info
| Function | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Protein Name | Interferon Alpha-21Ifn-Alpha-21Interferon Alpha-FLeif F |
| Database Links | Reactome: R-HSA-909733Reactome: R-HSA-912694Reactome: R-HSA-933541Reactome: R-HSA-9705671Reactome: R-HSA-983231Reactome: R-HSA-9833109 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interferon Alpha-21 proteinIfn-Alpha-21 proteinInterferon Alpha-F proteinLeif F proteinIFNA21 protein |
Information sourced from Uniprot.org