| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.01 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.10‑0.42 ng/mL, corresponding to a specific activity of 2.38×106~1.0×107 units/mg. |
| Gene Symbol: | IFNA8 |
| Gene ID: | 3445 |
| Uniprot ID: | IFNA8_HUMAN |
| Immunogen Region: | Ser24-Glu189 |
| Immunogen: | Recombinant Human IFN-alpha B2/IFNA8 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser24-Glu189) of Human IFN-alpha B2/IFNA8 (Accession #NP_002161.2) fused with a His tag at the C-terminus. |
| Immunogen Sequence: | CCHPRLSLHRPALEDLLLGS EANLTCTLTGLRDASGVTFT WTPSSGKSAVQGPPERDLCG CYSVSSVLPGCAEPWNHGKT FTCTAAYPESKTPLTATLSK SGNTFRPEVHLLPPPSEELA LNELVTLTCLARGFSPKDVL VRWLQGSQELPREKYLTWAS RQEPSQGTTTFAVTSILRVA AEDWKKGDTFSCMVGHEALP LAFTQKTIDRLADWQMPPPY VVLDLPQETLEE |
| Function | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Protein Name | Interferon Alpha-8 Ifn-Alpha-8 Interferon Alpha-B Leif B Interferon Alpha-B2 |
| Database Links | Reactome: R-HSA-909733 Reactome: R-HSA-912694 Reactome: R-HSA-933541 Reactome: R-HSA-9705671 Reactome: R-HSA-983231 Reactome: R-HSA-9833109 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interferon Alpha-8 protein Ifn-Alpha-8 protein Interferon Alpha-B protein Leif B protein Interferon Alpha-B2 protein IFNA8 protein |
Information sourced from Uniprot.org