Human IDH3G protein (Recombinant) (His-Tag) (STJP017448)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human IDH3G-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 50% Glycerol, 0.2M NaCl, 5mM DTT, 2mM EDTA |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IDH3G |
| Gene ID | 3421 |
| Uniprot ID | IDH3G_HUMAN |
| Accession Number | NP_004126 |
| Immunogen | Human |
| Immunogen Region | 40-393aa |
| Immunogen Sequence |
Additional Info
| Function | Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. |
| Protein Name | Isocitrate Dehydrogenase Nad Subunit Gamma - MitochondrialIsocitric Dehydrogenase Subunit GammaNad(+-Specific Icdh Subunit Gamma |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Isocitrate Dehydrogenase Nad Subunit Gamma - Mitochondrial proteinIsocitric Dehydrogenase Subunit Gamma proteinNad(+-Specific Icdh Subunit Gamma proteinIDH3G protein |
Information sourced from Uniprot.org