Human IDH1 (IDH1) Antibody Pair (STJAP00878)
General Information
| Short Description | This IDH1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R04-4K-8/R06-5P-1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | IDH1 |
| Gene ID | 3417 |
| Uniprot ID | IDHC_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Post Translational Modifications | Acetylation at Lys-374 dramatically reduces catalytic activity. |
| Function | Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency. |
| Protein Name | Isocitrate Dehydrogenase Nadp CytoplasmicIdhIdh1Cytosolic Nadp-Isocitrate DehydrogenaseIdpcNadp(+-Specific IcdhOxalosuccinate Decarboxylase |
| Database Links | Reactome: R-HSA-2978092Reactome: R-HSA-389542Reactome: R-HSA-6798695Reactome: R-HSA-9033241Reactome: R-HSA-9818025 |
| Cellular Localisation | CytoplasmCytosolPeroxisome |
| Alternative Antibody Pair Names | Isocitrate Dehydrogenase Nadp Cytoplasmic antibody pairIdh antibody pairIdh1 antibody pairCytosolic Nadp-Isocitrate Dehydrogenase antibody pairIdpc antibody pairNadp(+-Specific Icdh antibody pairOxalosuccinate Decarboxylase antibody pairIDH1 antibody pairPICD antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human IDH1 (IDH1) Antibody Pair (STJAP00878)
This antibody pair is designed to detect human IDH1 (Isocitrate Dehydrogenase 1, UniProt O75874). Reactivity has been confirmed for human samples only.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated and affinity purified, formulated in 0.01M PBS at pH 7.2. Clone IDs are R04-4K-8 and R06-5P-1 respectively.
This antibody pair has been validated for use in ELISA. No other assay formats are listed for this product.
Concentration information is not specified for this product. Working dilutions for both the capture and detection antibodies should be determined by the end user through titration optimization.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C. Repeated freeze/thaw cycles should be avoided to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.