Human ICAM3 (ICAM3) Antibody Pair (STJAP00877)
General Information
| Short Description | This ICAM3 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R02-4M-5/R05-3Q-7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | ICAM3 |
| Gene ID | 3385 |
| Uniprot ID | ICAM3_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Leukocytes. |
| Post Translational Modifications | Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated.glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages. |
| Protein Name | Intercellular Adhesion Molecule 3Icam-3Cdw50Icam-RCd Antigen Cd50 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-216083Reactome: R-HSA-5621575 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Pair Names | Intercellular Adhesion Molecule 3 antibody pairIcam-3 antibody pairCdw50 antibody pairIcam-R antibody pairCd Antigen Cd50 antibody pairICAM3 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human ICAM3 (ICAM3) Antibody Pair (STJAP00877)
This antibody pair is designed to detect human ICAM3 (Intercellular Adhesion Molecule 3), corresponding to UniProt entry P32942. Reactivity has been confirmed for human samples only.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated and affinity purified, formulated in 0.01M PBS at pH 7.2. Clone IDs are R02-4M-5 and R05-3Q-7 respectively.
This pair has been validated for use in ELISA. No other assay formats are specified in the product documentation.
Both antibodies were raised against a recombinant protein immunogen corresponding to human ICAM3. No further detail on the immunogen region is provided in the current product specification.
Both components should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C, and avoid repeated freeze/thaw cycles to maintain activity.
Optimal working concentrations for both the capture and detection antibodies are to be determined by the end user. No pre-specified dilution range is provided in the current product datasheet.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.