Human ICAM-2/CD102 protein (Recombinant) (His-Tag) (STJP018742)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018742
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General Information

Short DescriptionRecombinant-Human ICAM-2/CD102-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolICAM2
Gene ID3384
Uniprot IDICAM2_HUMAN
Accession NumberNP_001093259
ImmunogenHuman
Immunogen Region22-223aa
Immunogen SequenceSDEKVFE VHVRPKKLAV EPKGSLEVNC STTCNQPEVG GLETSLDKIL LDEQAQWKHY LVSNISHDTV LQCHFTCSGK QESMNSNVSV YQPPRQVILT LQPTLVAVGK SFTIECRVPT VEPLDSLTLF LFRGNETLHY ETFGKAAPAP QEATATFNST ADREDGHRNF SCLAVLDLMS RGGNIFHKHS APKMLEIYEP VSDSQ

Additional Info

Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Protein Name Intercellular Adhesion Molecule 2
Icam-2
Cd Antigen Cd102
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-5621575
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Microvillus
Co-Localizes With Rdx
Ezr And Msn In Microvilli
Alternative Protein Names Intercellular Adhesion Molecule 2 protein
Icam-2 protein
Cd Antigen Cd102 protein
ICAM2 protein

Information sourced from Uniprot.org

Citations

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