Human I-TAC/CXCL11 protein (Recombinant) (His-Tag) (STJP017420)

Name: Human I-TAC/CXCL11 protein (Recombinant) (His-Tag) (STJP017420)
SKU: STJP017420
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017420

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Short Description	Recombinant-Human I-TAC/CXCL11-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 10mM Sodium Citrate buffer (pH 3.5) containing 2mM DTT, 20% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)

Gene Symbol	CXCL11
Gene ID	6373
Uniprot ID	CXL11_HUMAN
Accession Number	NP_005400
Immunogen	Human
Immunogen Region	22-94aa
Immunogen Sequence	FPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF

Tissue Specificity	High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.
Function	Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
Protein Name	C-X-C Motif Chemokine 11 Beta-R1 H174 Interferon Gamma-Inducible Protein 9 Ip-9 Interferon-Inducible T-Cell Alpha Chemoattractant I-Tac Small-Inducible Cytokine B11
Database Links	Reactome: R-HSA-380108 Reactome: R-HSA-418594
Cellular Localisation	Secreted
Alternative Protein Names	C-X-C Motif Chemokine 11 protein Beta-R1 protein H174 protein Interferon Gamma-Inducible Protein 9 protein Ip-9 protein Interferon-Inducible T-Cell Alpha Chemoattractant protein I-Tac protein Small-Inducible Cytokine B11 protein CXCL11 protein ITAC protein SCYB11 protein SCYB9B protein

Information sourced from Uniprot.org