Human HTRA3 protein (Recombinant) (N-His) (STJP011506)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HTRA3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HTRA3 |
| Gene ID | 94031 |
| Uniprot ID | HTRA3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn141-Pro333 |
Additional Info
| Function | Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization. |
| Protein Name | Serine Protease Htra3High-Temperature Requirement Factor A3Pregnancy-Related Serine Protease |
| Database Links | |
| Cellular Localisation | SecretedSecretion Increased During Decidualization Of Endometrial Stromal Cells |
| Alternative Protein Names | Serine Protease Htra3 proteinHigh-Temperature Requirement Factor A3 proteinPregnancy-Related Serine Protease proteinHTRA3 proteinPRSP protein |
Information sourced from Uniprot.org